Transcript Klug9chapt24

Art and Photos in PowerPoint®
Concepts of Genetics
Ninth Edition
Klug, Cummings, Spencer, Palladino
Chapter 24
Applications and Ethics of Genetic
Engineering and Biotechnology
Copyright
© 2009©Pearson
Education,
Inc.
Copyright
2009 Pearson
Education,
Inc.
24.1
Genetically Engineered Organisms
Synthesize a Wide Range of
Biological and Pharmaceutical
Products
24.1.1
Insulin Production in Bacteria
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 24.1
24.1
Genetically Engineered Organisms
Synthesize a Wide Range of
Biological and Pharmaceutical
Products
24.1.2
Transgenic Animal Hosts and Pharmaceutical
Products
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Table 24.1
24.1
Genetically Engineered Organisms
Synthesize a Wide Range of
Biological and Pharmaceutical
Products
24.1.3
Recombinant DNA Approaches for Vaccine
Production and Transgenic Plants with Edible
Vaccines
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 24.2
24.2
Genetic Engineering of Plants Has
Revolutionized Agriculture
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 24.3
Copyright © 2009 Pearson Education, Inc.
Figure 24.4
24.2
Genetic Engineering of Plants Has
Revolutionized Agriculture
24.2.1
Transgenic Crops for Herbicide and Pest
Resistance
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 24.5
Copyright © 2009 Pearson Education, Inc.
Figure 24.6
24.2
Genetic Engineering of Plants Has
Revolutionized Agriculture
24.2.2
Nutritional Enhancement of Crop Plants
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 24.7
24.3
Transgenic Animals with Genetically
Enhanced Characteristics Have the
Potential to Serve Important Roles in
Agriculture and Biotechnology
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 24.8
Copyright © 2009 Pearson Education, Inc.
Figure 24.9
Copyright © 2009 Pearson Education, Inc.
Figure 24.10
24.4
Genetic Engineering and Genomics
Are Transforming Medical Diagnosis
24.4.1
Genetic Tests Based on Restriction Enzyme
Analysis
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 24.11
10 -12 weeks
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 24.12
24.4
Genetic Engineering and Genomics
Are Transforming Medical Diagnosis
24.4.2
Genetic Tests Using Allele-Specific
Oligonucleotides
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 24.13
Copyright © 2009 Pearson Education, Inc.
Figure 24.13a
Copyright © 2009 Pearson Education, Inc.
Figure 24.13b
Copyright © 2009 Pearson Education, Inc.
Figure 24.14
Copyright © 2009 Pearson Education, Inc.
Figure 24.15
24.4
Genetic Engineering and Genomics
Are Transforming Medical Diagnosis
24.4.3
Genetic Testing Using DNA Microarrays and
Genome Scans
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 24.16
Copyright © 2009 Pearson Education, Inc.
Figure 24.17
Copyright © 2009 Pearson Education, Inc.
Figure 24.18
Copyright © 2009 Pearson Education, Inc.
Figure 24.19
Copyright © 2009 Pearson Education, Inc.
Figure 24.19a
Copyright © 2009 Pearson Education, Inc.
Figure 24.19b
24.4
Genetic Engineering and Genomics
Are Transforming Medical Diagnosis
24.4.4
Genetic Analysis Using Gene Expression
Microarrays
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 24.20
Copyright © 2009 Pearson Education, Inc.
Figure 24.20a
Copyright © 2009 Pearson Education, Inc.
Figure 24.20b
Copyright © 2009 Pearson Education, Inc.
Figure 24.20c
Copyright © 2009 Pearson Education, Inc.
Figure 24.21
24.4
Genetic Engineering and Genomics
Are Transforming Medical Diagnosis
24.4.5
Application of Microarrays for Gene
Expression and Genotype Analysis of
Pathogens
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 24.22
Copyright © 2009 Pearson Education, Inc.
Figure 24.23
24.5
Genetic Engineering and Genomics
Promise New, More Targeted Medical
Therapies
24.5.1
Pharmacogenomics and Rational Drug
Design
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 24.24
24.5
Genetic Engineering and Genomics
Promise New, More Targeted Medical
Therapies
24.5.2
Gene Therapy
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 24.25
Copyright © 2009 Pearson Education, Inc.
Figure 24.26
Copyright © 2009 Pearson Education, Inc.
Figure 24.27
Copyright © 2009 Pearson Education, Inc.
Figure 24.28
Copyright © 2009 Pearson Education, Inc.
24.6
DNA Profiles Help Identify Individuals
24.6.1
DNA Profiling Based on DNA Minisatellites
(VNTRs)
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 24.29
24.6
DNA Profiles Help Identify Individuals
24.6.2
DNA Profiling Based on Microsatellites
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 24.30
Copyright © 2009 Pearson Education, Inc.
Figure 24.31
Copyright © 2009 Pearson Education, Inc.
Figure 24.31a
Copyright © 2009 Pearson Education, Inc.
Figure 24.31b
24.6
DNA Profiles Help Identify Individuals
24.6.3
Terrorism and Natural Disasters Force
Development of New Technologies
Forensic Applications of DNA Profiling
24.6.4
Copyright © 2009 Pearson Education, Inc.
24.7
Genetic Engineering, Genomics, and
Biotechnology Create Ethical, Social,
and Legal Questions
24.7.1
Concerns About Genetically Modified
Organisms and GM Foods
Genetic Testing and Ethical Dilemmas
The Ethical Concerns Surrounding Gene
Therapy
The Ethical, Legal, and Social Implications
(ELSI) Program
DNA and Gene Patents
24.7.2
24.7.3
24.7.4
24.7.5
Copyright © 2009 Pearson Education, Inc.