Proportion of admissions related to Adverse Drug Events 13% 22% Definite Contributing Not related 65%

Medication review using the ‘pill pruner’

`Pill pruner’

• • • • • • • •

Diuretics (Loop, thiazides) Vasodilators (calcium antagonists, α-blockers) Anti-platelet CNS medications (TCA, benzo,antipsychotics, SSRI) Anticholinergics Antihistamines NSAIDS Proton pump inhibitors

Frequency of drugs stopped/ reduced • Cardiovascular drugs – Vasodilators & β blockers – – – – Diuretics (loop, thiazides) Antiplatelets & anticoagulant ACEI Statins 66 57 50 32 30 • • • CNS medications Proton pump inhibitor Others (e.g. laxatives, analgesics, Ca ) 36 16 182