Transcript scleroderma

Classification of sclerodermas
• Localized sclerodermas
• Morhpea
• Linear scleroderma
Morphea
Linear scleroderma
Classification of sclerodermas
• Localized sclerodermas
• Morhpea
• Linear scleroderma
• Overlap syndromes (with SLE, myositis)
Classification of sclerodermas
• Localized sclerodermas
• Morhpea
• Linear scleroderma
• Overlap syndromes (with SLE, myositis)
• Scleroderma-like syndromes
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Eosinophilic fasciitis
Scleromyxedema
Chronic graft versus host
Drug-induced (bleomycin, toxic oil, tryptophan)
Eosinophilic fasciitis
(early)
Eosinophilic fasciitis
(late)
Scleromyxedema
Classification of sclerodermas
• Localized sclerodermas
• Morhpea
• Linear scleroderma
• Overlap syndromes (with SLE, myositis)
• Scleroderma-like syndromes
• Systemic sclerosis
• Diffuse cutaneous scleroderma
• Limited cutaneous scleroderma
• CREST syndrome
Diffuse vs Limited
Scleroderma-- Definitions
• Diffuse cutaneous scleroderma:
– Thick skin distal AND proximal to elbows and knees,
with or without the face (widespread, or diffuse, skin
thickening).
• Limited cutaneous scleroderma:
– Thick skin distal, but NOT proximal, to elbows and
knees, with or without the face (limited skin
thickening)
Thick skin
of torso
(diffuse
scleroderma)
Thick skin of fingers and hands
(limited scleroderma)