Transcript Supramolecular Encapsulation of Bio

Supramolecular Encapsulation of Bio-Inspired
Models by Cucurbiturils: Progress Report
Cátia Parente Carvalho
Uwe Pischel (UHU)
José Paulo da Silva (UALG)
SUPRABIOENCAPS
Aim:
 Development of new fluorescent molecules for marking of nanocapsules
Guest
Host
Supramolecular Complex
A novel fluorophore-anchor dye has been designed and characterised with respect
to its ability to form supramolecular host-guest complexes with cucurbit[6]uril and
cucurbit[7]uril .
CB[n]
Aminonaphthalimide-Putrescine
Complex formation between the
Aminonaphthalimide-Putrescine•Cucurbit[n]uril
Complex formation:
Absorption spectroscopy
Fluorescence spectroscopy
Mass spectrometry
RMN
• Sensor for Biogenic Amines
Supramolecular Complex
Amine
(Guest 2)
Guest 1
Change of Fluorescence
Supramolecular Complex 2