Transcript Abdominal Aortic Aneurysm

Abdominal Aortic
Aneurysm
Bryan Imayanagita
UCI T-RAP
2/2/11
Background
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Aka: AAA
Aneurysm: swelling/dilation
Most common in men over 60. smoking
increases risk
Rupture most dangerous complication
Pathophysiology
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Degredation of tuncia media
Metalloproteinases destroy elastin making aortic
wall more susceptible to change in BP
Abdominal aorta contains less elastin compared
with the thoractic aorta; higher chance in
abdomen for aneurysm
Age causes decline in elastin
90% infrarenally
Causes
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Smoking
Atherosclerosis
Heredity
Hypertension
High cholesterol
Trauma
Symptoms
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Often asymptomatic
Can manifest as back, abdomen, groin pain
Palpable abdominal mass upon examination
Diagnosis
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Physical examination
CT/Ultrasound
MRI and Angiography used less often
Treatment
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Conservative:
Surgery more risky
 Lifestyle changes: cholesterol meds, stop smoking,
etc.
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Surgical:
Endovascular stent insertion
 Open surgery
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Stent Insertion
Open Repair
Prognosis
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s/p mortality 40% for ruptured AAA
Pre-rupture surgery: 1-6%
Sources
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http://my.clevelandclinic.org/disorders/aneurys
ms/hic_abdominal_aortic_aneurysm.aspx
http://emedicine.medscape.com/article/463354
-overview
http://www.mayoclinic.org/aortic-aneurysm/
http://www.nlm.nih.gov/medlineplus/ency/arti
cle/000162.htm