Clayton Biotechnologies, Inc. is a for

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Transcript Clayton Biotechnologies, Inc. is a for

Overview of Clayton Biotechnologies, Inc.

Clayton Biotechnologies, Inc.

One Riverway, Suite 1520 Houston, Texas 77056 713.963.5860

www.claytonbiotech.com

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Clayton Biotechnologies, Inc. is a for-profit company which facilitates the commercialization of medical discoveries made by the Clayton Foundation for Research and its supporting entities.

The Clayton Foundation for Research is a nonprofit medical research organization in

Houston, Texas established in 1933 by Benjamin Clayton.

The mission of the Foundation is two-fold:

To conduct medical research for the purpose of discovering the cause, prevention and cure of diseases for the benefit of mankind, and To transfer the resulting medical research discoveries from the laboratory to the use of the general public by patenting and licensing such technology for development into drugs or other products.

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We conduct and fund medical research programs at leading universities, hospitals and academic institutions

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Baylor College of Medicine Baylor College of Medicine Texas Children's Cancer Center North Carolina State University Oregon Health and Science University Salk Institute for Biological Studies The University of Texas at Austin The University of Texas Health Science Center at San Antonio The University of Texas M.D. Anderson Cancer Center The University of Texas Medical Branch at Galveston The University of Texas Southwestern Medical Center at Dallas University of California, San Diego University of Geneva 3

Leading Researchers

ANTIBODIES & ONCOLOGY

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George Georgiou Jordan Gutterman Stephen Howell Brent Iverson Beat Imhof Bert O’Malley Donald Parsons Michael Rosenblum Hongtao Yu METABOLIC DISEASES

Marc Montminy

David Russell CNS & OPHTHAMOLOGY

Kuo-Fen Lee

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Karl-Heinz Krause Paul Sawchenko Tim Stout VIROLOGY and MICROBIOLOGY

Dennis Brown and Raquel Hernandez

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Jere McBride and David Walker Haley Tucker and James Walker OTHER

Marc Feldman and Thomas Milner

David Corry 4

Some of our start-up companies

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Some of our Other Licensees

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Products Brought to the Market

Therapeutics AccuPlex™4 test Diagnostics SCA6 diagnostic tests Complete Ataxia Evaluation 7

Collaboration and Licensing Opportunities

Antibody targets for cancer: Grp78; Srpx2, Olmfl-3

Alk4-Fc, a Cripto antagonist for Cancer

Granzyme B - a potent payload for antibody drug conjugates (ADC)

Antibody Fc engineering: aglycosylated antibodies with potent and specific effector function

Avicins, new class of triterpenes to treat cancer – IND approved package

Filaggrin to treat dermatological disorders

RTEF therapy for ocular neovascular disease

Vaccines and Diagnostics for Ehrlichioses

Synergistic activation of beta-islet cell production

CRFR1 and CRFR2 agonists for Diabetes

CRFR1 antagonists - therapeutic for early onset AD 8

Please contact us!

Clayton Biotechnologies, Inc.

One Riverway, Suite 1520 Houston, Texas 77056 713.963.5860

www.claytonbiotech.com

[email protected]

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