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A novel CBT informed intervention for social anxiety in people recovering from psychosis.

Ruth Turner, Richard White, Rebecca Lower, Lina Gega, David Fowler

Acknowledgements

• Everyone who has helped to make the Social Anxiety Research Clinic successful: Tony Reilly,Timothy Clarke, Felicity Waite, Evelina Medin, Kevin Lloyd, Rose Christopher, Emily Drake all of our participants,and the case managers within Central Norfolk Early Intervention Team

Social Anxiety Research Clinic • Describe participants • Brief description of intervention • Describe findings • Discussion of use of virtual environments

Background

• Up to 70% of people recovering from psychosis experience social anxiety.

• This is a significant barrier to social recovery.

• Social anxiety appears to be independent of the experience of positive symptoms

Study outline

Screen referred cases for eligibility Enrollment and Consent Procedure Baseline Assessment (N = 48)

Social anxiety Cognitive bias assessment Schema, low-level psychotic symptoms Qualitative interview Exclude non-consenters and cases not meeting inclusion criteria

Allocated to CBT (N = 12) Treatment Group (N=24) immediate standard Randomisation by randomly ordered sealed envelopes Allocated to immediate enhanced CBT (N = 12) Allocated to CBT (N = 12) Waitlist control delayed standard (N=24) Allocated to delayed enhanced CBT (N = 12)

Assess primary/secondary outcomes at the end of the intervention period (12 weeks) Assess primary outcome 6 weeks following end of intervention (18 weeks) Wait for 12 weeks Assess primary/secondary outcomes at the end of the 12 week wait Assess primary outcome at 18 weeks Assess primary/secondary outcomes at 24 weeks Assess primary outcome 12 weeks following end of intervention (24 weeks) Receive standard CBT for 8-12 sessions Receive enhanced CBT for 8-12 sessions

Description of sample at baseline

• Demographics: ; 17 male, 5 female; Average age = 26 (S.D. 6) • PANSS (data for 13 participants) average score on positive sub-scale = 10.9 (S.D. = 3.0). 46% (n = 6) of participants scored 4 or more on one or more items of the sub-scale.

• BDI average score = 26.6 (S.D. 15.8) • SIAS: SARC Social Phobia Comparison Non-Clinical Comparison SIAS M (S.D.) 55.6 (10.7) 34.6 (16.4) 18.8 (11.8)

Description of sample at baseline

SSI SARC Psychosis Comparison Non-Clinical SSI SA M (S.D.) 17.4 (4.7) 8.6 (6.7) 4.4 (5.1) SSI P M (S.D.) 11.5 (7.6) 6.0 (6.4) 2.9 (3.6) SSI AE M (S.D.) 8.4 (5.5) 4.1 (5.7) 2.3 (3.4) BCSS Positive Self Negative Self M (S.D.) M (S.D.) SARC 6.8 (6.4) Psychosis Comparison 10.3 (6.4) Non-clinical 10.2 (4.2) 9.2 (7.0) 7.2 (5.9) 3.5 (3.5) Positive Other M (S.D.) 8.6 (6.5) 10.3 (6.0) 10.4 (4.5) SSI total M (S.D.) 37.2 (15.0) 18.7 (15.7) 9.5 (9.2) Negative Other M (S.D.) 9.0 (7.7) 9.1 (6.8) 4.0 (4)

Formulation

Trigger

People talking Performance/ expectations on me Based on Clarke and Wells model

Activates Beliefs and Assumptions

I am inadequate I have to be on guard or I will be hurt Others are judgemental

Perceived Social Danger

Others might be talking about me I will be found out and punished

Processing self as social object

Focus on own anxiety Image – self sweating

Safety Behaviour

Avoid social and performance situations Listen in to others’ conversations

Anxiety

Sweating Heart racing Could not concentrate

Intervention

• The intervention is an assisted self-help intervention which follows four stages: – first stage included an assessment of social anxiety, goal setting and psycho-education about social anxiety.

– Stage two helped patients develop an individualised CBT formulation. Patients identified their own idiosyncratic safety behaviours.

– Stage three involved repeated exposure to anxiety provoking social situations in the format of behavioural experiments – The final stage focussed on maximising patients’ gains by planning further exposure-based behavioural experiments which were done either independently by the patient or with support from the care team.

• Additional interventions were piloted using computerised cognitive bias modification and virtual environments.

Outcomes - SIAS

• Baseline SIAS scores were compared to those at the 12, 18 and 24 week follow up points.

Baseline 12 weeks 18 weeks Therapy Waitlist 24 weeks 60.2 (11.19) 49.7 (12.23) 42.9 (8.15) 40.4 (10.95) 52.4 (9.19) 52.1 (13.69) 52.1 (12.76) 50.6 (13.09)

Outcome - SIAS

Therapy Waitlist N Mean change score (SD) Reliable improvement (n) Reliable deterioration (n) Clinically significant reliable change (n) N Mean change score (SD) Reliable improvement (n) Reliable deterioration (n) Clinically significant reliable change (n) 11 -.27 (11.34) 3 3 2 0 2 12 week 10 -10.50 (8.90) 6 0 1 18 week 7 -17.29 (4.86) 7 0 4 24 week 8 -16.75 (13.75) 6 9 -.56 (7.45) 1 1 1 8 -1.0 (10.52) 3 3 1

Additional pilot interventions

• Preliminary evidence that CBM-I sentence completion task can be used to train a more positive interpretation bias in this group.

• Virtual environments are being used to provide additional situations in which behavioural experiments can be conducted.

CAFÉ “sitting down waiting to order”

Conclusions

• Preliminary evidence that an assisted self help intervention may help to reduce the level of social anxiety in people recovering from psychosis.

• Psychoeducation about social anxiety and the active engagement in behavioural experiments seems to be key.

Any questions?

[email protected]