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ProDerma Therapeutics
tm
ProDerma
today for healthier skin tomorrow
The information in this presentation is proprietary and can only be reproduced with the permission of ProDerma Therapeutics, LLC, Inc. January 2011
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ProDerma
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Who is our client?
• Dermatology Offices
• Plastic Surgeon Offices
• Medical Spas
• Destination Spas
• OBGYN
• General Practice Medical Offices
• Professional setting with a licensed Esthetician or M.D.
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ProDerma
tm
Product Knowledge
Application Techniques
ProDerma Foundation
• Dispense a small amount of ProDerma foundation using a wedge
sponge, fingertips, or foundation brush and blend where needed.
• One application gives a smooth, natural look, or apply in buildable
layers for more complete coverage
ProDerma Concealers
• Dispense a small amount of ProDerma Concealers using a wedge
sponge, fingertips, or concealers brush and blend where needed.
• Use sparingly to camouflage problem areas
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ProDermatm
Product Knowledge
• Use to camouflage after most cosmetic
procedures to effectively cover bruising
and redness, reducing patient down time
• Vitamins A, C and E (powerful antioxidants)
help increase collagen and protect from
environmental damage
• Evens out skin tone
• Water resistant for up to 90 minutes in water
• Camouflages hyper pigmentation, tattoos
and scars
• Transfer resistant so will not rub off on clothes
• SPF 30 helps protect skin from environmental
damage
• Non-comedogenic helps skin to breath
• Only foundation that allows your skin to
breathe unlike other foundations today that
suffocate and exacerbate problematic skin
• Soothes inflammation
• Stimulates collagen production
• Non-irritating to acne and rosacea
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ProDerma
tm
Product Knowledge
Active Ingredients & their Benefits
• ProDerma Oxygenating Peptide Complex Complex Actives:
•Sodium Hyaluronate, Zinc PCA, Water, Saccharomyces Lysae Extract, Algae Extract, Artemisia Vulgaris
Extract, Butylene G ProDerma Oxygenating Peptide Complex, Sea Whip Extract
• ProDerma Oxygenating Peptide Complex Complex benefits:
•A skin respiratory factor that increases oxygen uptake by skin cells
•Works at the cellular level to soothe inflammation and protect from environmental toxins, while stimulating
collagen production
•ProDerma Foundation and Concealer Actives
•Titanium Dioxide 6.4%, Zinc Oxide 10.0%
•ProDerma Foundation and Concealer benefits
•Protection from UVA/UVB rays
•ProDerma Acne Foundation and Concealer Actives
•Titanium Dioxide 7.0%, Zinc oxide 5.9%, Salicylic Acid 2.0%
•ProDerma Foundation and Concealer benefits
•Protection from UVA/UVB rays
•Salicylic Acid treats acne
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A Unique Delivery System
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Triple silica open mesh delivery system
Upon application, unique volatile esters
evaporate leaving behind a breathable
mesh that is both water and transfer
resistant.
Openings allow air to pass through the
mesh and down into the skin below
The chemical structure of the mesh
causes it to be attracted to the surface
of the skin so it stays in place.
It provides an unusually smooth texture
on the skin while acting as a breathable
base to deliver ingredients
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ProDerma
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LYCD Live Yeast Cell Derivates
 Originally used in 1940’s as a burn
and wound ointment
 Breakthrough technology breathes
new life into this timeless ingredient
Ordinary baker’s yeast is stressed with
UV radiation
The cells respond by producing protective
polypeptides
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ProDerma
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Packaged for Special Delivery
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We harvest these protective
peptides and wrap them with an
organic coating creating a particle
that can be suspended in our
breathable mesh.
By floating or suspending the
particle in our breathable mesh,
we ensure the outside air still
gets through.
Upon application, the coated
particle is actually attracted out of
the mesh by the keratinocytes.
Once on the surface, the particles
deliver their polypeptide payload
to help the skin respond to
inflammation and recover.
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Polypeptides Delivering Support
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Polypeptides increase cell respiration
 Increased collagen synthesis
 Increased elastin synthesis
 Increased cell respiration allows
cells to better utilize the vitamin A
C and E that ProDerma provides
Increased synthesis of hyaluronic acid.
Polypeptides promote the soothing of
inflammed tissue.
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The Recovery Role for LYCD Polypeptides
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Superoxide dismutase (SOD)
 Superoxide dismutase is a natural antioxidant.
 Once the free radicals have finished their job combating infection and
disposing of debris, they must be inactivated to start the actual healing
process.
 SOD and other antioxidants scavenge the free radicals and promote the
healing and repair process.
 Depletions of up to 70% in SOD and other antioxidants such as vitamins C
and E have been reported after an injury.
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The Recovery Role for LYCD Polypeptides
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Ubiquitin is a heat shock protein
 Signaling role in regulating growth and differentiation of specific
lymphocytes or hematopoietic cells
 Cell surface receptors regulated by ubiquination
 T cell receptors
 Growth hormone receptors
 IgE surface receptors
 Macrophages
 Platelet-derived growth factors (PDGF) receptors
Yeast protein fragment HSP12/GLP1
 Maintain protein homeostasis by alleviating protein misfolding defects
and aggregation
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ProDerma
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Oxygenating Peptide Complex
•Polypeptides from LYCD increase cell respiration
•Increased collagen synthesis
•Increased elastin synthesis
•Increased cell respiration allows cells to better utilize the vitamin A C and E that ProDerma
Breathable Foundation provides
•Increased synthesis of hyaluronic acid.
•Polypeptides promote the soothing of inflamed tissue.
ProDerma Breathable Foundation Anti-Aging and Acne also contains a complex of other polypeptides
such as:
•An anti-aging skin care complex combining the activity of Palmitoyl Hexapeptide-14 and plant derived
glycoconjugates (Goji berry extract) for a maximum synergistic effect rebuilding skin's extra cellular matrix.
Multiple rebuilding pathways are activated including: collagen biosynthesis, fibroblast proliferation and
inhibition of destructive matrix metalloproteinases. Anti-aging visible results can be seen in reduction of
lines and wrinkles along with an improvement in skin's elasticity.
•A unique delivery matrix that combines a redness and inflammatory diminishing peptide with the antioxidant properties of tea, the calming properties of boswellia serrata and the soothing quality of honey.
Tetrapeptide-14 is a specific peptide sequence that can is used to alleviate the redness associated with
rosacea or mild sun exposure. Acts by down regulating interleukin-6 (IL-6) to prevent inflammation, which
in turn reduces MMP-1 damage with the net effect of a bright and even skin appearance.
Also reduces likelihood of post inflammatory pigmentation along with improving overall skin
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ProDerma
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Increased Blood Flow
Respiration is the process by which the cells of an organ utilize oxygen and nutrients needed
for efficient metabolism and health. It also includes the process by which the skin eliminates
carbon dioxide and toxic elements before damage can occur. As both intrinsic damage (natural
aging) and extrinsic damage (sun and pollution exposure) become apparent in your
appearance, the blood vessels of the skin become impaired in their ability to function properly.
The decrease in blood flow also creates a decrease in metabolism due to a decrease in the
delivery of oxygen.
ProDerma Breathable foundation contains a complex of Panax Ginseng and Gynostemma
pentaphllum extracts which increase respiration and protect and nourish dry skin.
Ginsengosides, the active component of ginseng, are known to enhance circulation in the
capillaries of the skin and increase the supply of nutrients to the epidermis. Gynostemma also
enhances circulation and respiration as well as exhibiting strong anti-oxidant and antiinflammatory effects.
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ProDerma
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Dermal Respiratory Factor (LYCD)
Classified by the FDA as a wound-healing agent, LYCD (also called Biodyne), is a skin respiratory factor
that helps skin cells to promote the healing process through the uptake of oxygen.
It was patented by Dr.Sperti in 1939, who named it Biodyne because it stimulates healthy cell growth. The
word Biodyne comes from the Greek words bios (life) and dyne (force).
When cells experience injury or destruction, some will produce hormones which stimulate cellular
multiplication so that the tissues heal. It’s like a community picking up the pieces to help an individual in
trouble. Dr Sperti’s group, who discovered Biodyne, found that they were able to isolate a ‘reproductive
stimulating substance’ from the dead tissue. They were able to isolate three distinct substances:
•Those that accelerate the cellular metabolism of sugar
•Those that stimulate growth and reproduction
•Those that stimulate cell reproduction.
Collectively, these substances were named Biodynes.
Further research at the University of Cincinnati demonstrated that biodynes could be extracted from
heated yeast cells. This type of biodyne is called Live Yeast Cell Derivative (LYCD) and contains nutrients
such as proteins, amino acids, minerals, carbohydrates, nucleic acid and other gene products. The active
ingredient has even been isolated as a protein fraction containing a mixture of several peptides one of
which is a peptide fraction that stimulates wound healing. Biodyne is known to be biologically active on
skin cells. Clinical studies from the Cincinnati Burn Unit and Oregon University School of Medicine show
that Biodyne speeds wound healing in burns and post surgically.
Biodynes (LYCD) are also known as Skin Respiratory Factor and Tissue Respiratory Factor
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Clinical Reprint
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Available online
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Donna J. Schlemm, Maria J. Crowe, Redmond B. McNeill, Anne E. Stanley, Stephen
J. Keller (1999) Medicinal yeast extracts.
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Click below to read the full-text article
• http://dx.doi.org/10.1379%2F14661268%281999%29004%3C0171%3AMYE%3E2.3.CO%3B2
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tm
ProDerma
Summary
ProDerma’sTM patented, clinically proven triple silica gel base allows skin to breathe. Acne
system controls surface shine & helps prevent future breakouts
ProDerma Oxygenating Peptide Complex4 complex promotes cell recovery & regeneration
Clinically proven, non-irritating, chemical-free UVA/UVB helps protect against the harmful
effects of the sun
Flawless natural-looking coverage, doesn’t sink into fine lines & wrinkles, feels weightless &
lasts all day
The only anti-aging system that promotes healing, anti-aging, increases oxygen &
camouflages at the same time
The only acne control system that fights acne, controls surface shine, promotes healing &
camouflages skin blemishes at the same time.
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ProDerma
tm
Delivering Results
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Mesh provides an unusually
stable foundation providing a
base to suspend fine particles
 Color pigments
 Physical sunscreens
Coverage for today that improves
your skin’s health for tomorrow.
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Delivering post-procedure results, after 30%TCA Peel
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Delivering everyday results
Right side patient treated with
ProDerma Camouflage post severe
sunburn
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Post Rosacea Laser Treatment
Day Two
Middle untouched, Right and Left side treated with ProDerma
Camouflage
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Introducing New & Improved
Multi-Benefit
ProDerma
Anti-aging with the highest level of Zinc Oxide available in a foundation
10% Zinc Oxide protects skin from harmful effects of sun & accelerates recovery
Acne control
2% Salicylic Acid in a time release formulation delivers continuous treatment &
minimizes surface dryness & irritation
Increased Skin Hydration, Protection & Recovery
Bois II reduces trans-epidermal water loss
Stimulates membranes in outer layers of the stratum corneum
Protects skin’s barrier properties, essential to wound healing
With a Natural Wound Healer
Natural Wound Healer
Certified organic Aloe Vera soothes inflamed & irritated skin
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ProDerma Products
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Dr. Walton Montegut, MD
Newport Beach, CA
Laser Session
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