Transcript Erythron
Kitten with Pruritis
Dennis B. DeNicola, DVM, PhD, DACVP
Chief Veterinary Educator
IDEXX Laboratories
“Kitten” – 6 month old DSH
6 months old
Intact female
Domestic Shorthair
Presented with clinical history of pruritis
Cat was depressed upon presentation but became
extremely excited during blood collection process
“Kitten” – 6 month old DSH
WBC
LYM
MONO
NEU
EOS
BASO
%LYM
%MONO
%NEU
%EOS
%BASO
HCT
RBC
HGB
RETIC
=
=
=
=
=
=
=
=
=
=
=
=
=
=
=
17.76
2.36
1.78
12.29
1.29
0.05
13.3
10.0
69.2
7.2
0.3
23.9
6.11
8.5
102.8
K/L
K/L
K/L
K/L
K/L
K/L
%
%
%
%
%
%
M/L
g/dL
K/L
%RETIC
MCV
RDW
MCHC
MCH
PLT
MPV
PCT
PDW
=
=
=
=
=
=
=
=
=
1.7
39.1
22.7
35.5
13.86
905
16.69
1.5
17.9
%
fL
%
g/dL
pg
K/L
fL
%
%
5.50
0.90
0.10
2.50
0.10
0.00
– 19.50 )
– 7.00 )
– 0.79 )
– 12.50 )
– 0.79 )
– 0.10 )
LOW
( 30.0
( 5.00
( 8.0
–
45.0 )
– 10.00 )
–
15.1 )
LOW
HIGH
(
(
(
(
(
–
58.0 )
–
22.0 )
–
36.0 )
– 17.60 )
–
600 )
HIGH
HIGH
(
(
(
(
(
(
41.0
17.3
29.0
12.50
175
“Kitten” – 6 month old DSH
Erythron
HCT
RBC
HGB
RETIC
%RETIC
MCV
RDW
MCHC
MCH
=
=
=
=
=
=
=
=
=
23.9
6.11
8.5
102.8
1.7
39.1
22.7
35.5
13.86
%
M/L
g/dL
K/L
%
fL
%
g/dL
pg
LOW
( 30.0 – 45.0 )
( 5.00 – 10.00 )
( 8.0 – 15.1 )
LOW
HIGH
( 41.0 – 58.0 )
( 17.3 – 22.0 )
( 29.0 – 36.0 )
(12.50 – 17.60)
“Kitten” – 6 month old DSH
Erythron
HCT
RBC
HGB
=
=
=
23.9 %
6.11 M/L
8.5 g/dL
LOW
( 30.0 – 45.0 )
( 5.00 – 10.00 )
( 8.0 – 15.1 )
“Kitten” – 6 month old DSH
Erythron
HCT
RBC
HGB
=
=
=
Anemia
Mild
23.9 %
6.11 M/L
8.5 g/dL
LOW
( 30.0 – 45.0 )
( 5.00 – 10.00 )
( 8.0 – 15.1 )
“Kitten” – 6 month old DSH
Erythron
HCT
RBC
HGB
RETIC
%RETIC
=
=
=
=
=
23.9 %
6.11 M/L
8.5 g/dL
102.8 K/L
1.7 %
LOW
( 30.0 – 45.0 )
( 5.00 – 10.00 )
( 8.0 – 15.1 )
“Kitten” – 6 month old DSH
Erythron
HCT
RBC
HGB
RETIC
%RETIC
=
=
=
=
=
23.9 %
6.11 M/L
8.5 g/dL
102.8 K/L
1.7 %
LOW
Anemia
Mild, regenerative
( 30.0 – 45.0 )
( 5.00 – 10.00 )
( 8.0 – 15.1 )
“Kitten” – 6 month old DSH
Erythron
HCT
RBC
HGB
RETIC
%RETIC
MCV
RDW
MCHC
MCH
=
=
=
=
=
=
=
=
=
23.9
6.11
8.5
102.8
1.7
39.1
22.7
35.5
13.86
%
M/L
g/dL
K/L
%
fL
%
g/dL
pg
LOW
( 30.0 – 45.0 )
( 5.00 – 10.00 )
( 8.0 – 15.1 )
LOW
HIGH
( 41.0 – 58.0 )
( 17.3 – 22.0 )
( 29.0 – 36.0 )
(12.50 – 17.60)
“Kitten” – 6 month old DSH
Erythron
HCT
RBC
HGB
RETIC
%RETIC
MCV
RDW
MCHC
MCH
=
=
=
=
=
=
=
=
=
23.9
6.11
8.5
102.8
1.7
39.1
22.7
35.5
13.86
%
M/L
g/dL
K/L
%
fL
%
g/dL
pg
LOW
( 30.0 – 45.0 )
( 5.00 – 10.00 )
( 8.0 – 15.1 )
LOW
HIGH
( 41.0 – 58.0 )
( 17.3 – 22.0 )
( 29.0 – 36.0 )
(12.50 – 17.60)
Anemia
Mild, regenerative, microcytic and potential mild
anisocytosis
Erythron – Data Interpretation
Anemia
Mild
Microcytic (decreased MCV)
Regenerative (increased Reticulocyte Count)
Potential mild anisocytosis (increased RDW)
Erythron – Blood Film
Erythron – Blood Film
Erythron – Blood Film
Erythron – Blood Film
Erythron – Blood Film
Erythron – Blood Film
Erythron – Blood Film Interpretation
Anemia
Mild
Regenerative - reticulocytosis
Polychromasia
Anisocytosis
Erythron – Blood Film Interpretation
Anemia
Mild
Regenerative - reticulocytosis
Polychromasia
Anisocytosis
Blood loss anemia
Developing Iron deficiency
“Kitten” – 6 month old DSH
Leukon
WBC
=
LYM
=
MONO =
NEU
=
EOS
=
BASO =
%LYM =
%MONO =
%NEU =
%EOS =
%BASO =
17.76
2.36
1.78
12.29
1.29
0.05
13.3
10.0
69.2
7.2
0.3
K/L
K/L
K/L
K/L
K/L
K/L
%
%
%
%
%
HIGH
(
(
(
(
(
(
5.50 – 19.50 )
0.90 – 7.00 )
0.10 – 0.79 )
2.50 – 12.50 )
0.10 – 0..79 )
0.00 – 0.10 )
“Kitten” – 6 month old DSH
Leukon
WBC
=
( 5.50 – 19.50 )
17.76 K/L
High normal leukocyte count
“Kitten” – 6 month old DSH
Leukon
WBC
=
LYM
=
MONO =
NEU
=
EOS
=
BASO =
%LYM =
%MONO =
%NEU =
%EOS =
%BASO =
17.76
2.36
1.78
12.29
1.29
0.05
13.3
10.0
69.2
7.2
0.3
K/L
K/L
K/L
K/L
K/L
K/L
%
%
%
%
%
HIGH
(
(
(
(
(
(
5.50 – 19.50 )
0.90 – 7.00 )
0.10 – 0.79 )
2.50 – 12.50 )
0.10 – 0..79 )
0.00 – 0.10 )
“Kitten” – 6 month old DSH
Leukon
WBC
=
LYM
=
MONO =
NEU
=
EOS
=
BASO =
%LYM =
%MONO =
%NEU =
%EOS =
%BASO =
17.76
2.36
1.78
12.29
1.29
0.05
13.3
10.0
69.2
7.2
0.3
K/L
K/L
K/L
K/L
K/L
K/L
%
%
%
%
%
(
(
(
(
(
(
HIGH
5.50 – 19.50 )
0.90 – 7.00 )
0.10 – 0.79 )
2.50 – 12.50 )
0.10 – 0..79 )
0.00 – 0.10 )
High normal leukocyte count
Mild monocytosis
“Kitten” – 6 month old DSH
Leukon
WBC
=
LYM
=
MONO =
NEU
=
EOS
=
BASO =
%LYM =
%MONO =
%NEU =
%EOS =
%BASO =
17.76
2.36
1.78
12.29
1.29
0.05
13.3
10.0
69.2
7.2
0.3
K/L
K/L
K/L
K/L
K/L
K/L
%
%
%
%
%
(
(
(
(
(
(
HIGH
5.50 – 19.50 )
0.90 – 7.00 )
0.10 – 0.79 )
2.50 – 12.50 )
0.10 – 0..79 )
0.00 – 0.10 )
High normal leukocyte count
Mild monocytosis
Low normal lymphocytes in
face of excitement !
“Kitten” – 6 month old DSH
Leukon
WBC
=
LYM
=
MONO =
NEU
=
EOS
=
BASO =
%LYM =
%MONO =
%NEU =
%EOS =
%BASO =
17.76
2.36
1.78
12.29
1.29
0.05
13.3
10.0
69.2
7.2
0.3
K/L
K/L
K/L
K/L
K/L
K/L
%
%
%
%
%
(
(
(
(
(
(
HIGH
5.50 – 19.50 )
0.90 – 7.00 )
0.10 – 0.79 )
2.50 – 12.50 )
0.10 – 0..79 )
0.00 – 0.10 )
High normal leukocyte count
Mild monocytosis
Low normal lymphocytes in
face of excitement !
High normal eosinophils with
possible “stress”
Erythron – Blood Film
Erythron – Blood Film
Erythron – Blood Film
Erythron – Blood Film
Erythron – Blood Film
Erythron – Blood Film
Erythron – Blood Film
Erythron – Blood Film
Erythron – Blood Film
Leukogram Interpretation
Normal leukocyte count
No lymphocytosis in face of excitement
Probable underlying glucocorticoid influence (“stress”)
High normal eosinophil count in face of possible
glucocorticoid influence (“stress”)
High probability of underlying eosinophilic
inflammatory condition
“Kitten” – 6 month old DSH
WBC
LYM
MONO
NEU
EOS
BASO
%LYM
%MONO
%NEU
%EOS
%BASO
HCT
RBC
HGB
RETIC
=
=
=
=
=
=
=
=
=
=
=
=
=
=
=
17.76
2.36
1.78
12.29
1.29
0.05
13.3
10.0
69.2
7.2
0.3
23.9
6.11
8.5
102.8
K/L
K/L
K/L
K/L
K/L
K/L
%
%
%
%
%
%
M/L
g/dL
K/L
%RETIC
MCV
RDW
MCHC
MCH
PLT
MPV
PCT
PDW
=
=
=
=
=
=
=
=
=
1.7
39.1
22.7
35.5
13.86
905
16.69
1.5
17.9
%
fL
%
g/dL
pg
K/L
fL
%
%
5.50
0.90
0.10
2.50
0.10
0.00
– 19.50 )
– 7.00 )
– 0.79 )
– 12.50 )
– 0.79 )
– 0.10 )
LOW
( 30.0
( 5.00
( 8.0
–
45.0 )
– 10.00 )
–
15.1 )
LOW
HIGH
(
(
(
(
(
–
58.0 )
–
22.0 )
–
36.0 )
– 17.60 )
–
600 )
HIGH
HIGH
(
(
(
(
(
(
41.0
17.3
29.0
12.50
175