Practice Gene Mapping problems with KEY
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Transcript Practice Gene Mapping problems with KEY
Map Units
Snapdragons with genotypes CCDD and ccdd are
crossed. The CcDd progeny were then crossed with
ccdd plants and we obtain 30% CcDd, 20% ccD 20%
Ccdd and 30% ccdd offspring. We conclude
a. Genes C and D are linked, separated by 20 map
units
b. Genes C and D are linked, separated by 30 map
units
c. Genes C and D are linked, separated by 40 map
units
d. Genes C and D are unlinked
Answer:
CD= 30%
cd= 30%
Cd= 20%
cD= 20%
20% cD + 20% Cd = 40%
40% = 40 map units
Snapdragons with genotypes DDEE and ddee are
crossed. The DdEe progeny are then crossed with ddee
plants and we obtain 45% DdEe, 5 % ddEe, 5% Ddee
and 45% ddee. How far apart are genes D and E?
a. 5 map units
b. 10 map units
c. 45 map units
d. Genes D and E are not linked
Answer:
DE= 30%
de= 30%
De= 5%
dE= 5%
5 % dE + 5% De = 10%
10% = 10 map units
A bit tougher:
In fruit flies, there are 3 recessive mutations.
s = Scute (no thorax bristles) S = wild type
e = Echinus (rough eye surface) E = wild type
v = vestigial wings V = wild type
P: We cross homozygous recessive flies (sseevv) with
homozygous dominant wild type flies (SSEEVV)
F1:
All F1’s have the wild type phenoytype, and genetically
would be:
SsCcVv
To produce the F2:
Cross the F1 flies (SsCcVv) with recessive flies (ssccvv)
and you get an F2 with 6 different phenotypes:
Out of 1000 flies: + = wild type
Scute
Echinus
Vestigial
Total
scute
echinus
vestigial
420
+
+
+
435
scute
+
+
46
+
echinus
vestigial
44
scute
echinus
+
20
+
+
vestigial
25
scute
+
vestigial
6
+
echinus
+
4
Assignment:
From the genetic data, determine the
recombination frequencies between each
pair of genes (s/e , e/v, s/ v).
Using these frequencies, construct a
genetic map:
ANSWER:
s-e recombination
46+44+6+4= 100/1000= 10%
s-v recombination
46+44+20+25= 135/1000= 13.5%
e-v recombination
20+25+6+4= 55/1000= 5.5%
s
10 map units
e
v
5.5 map units