condyloma acuminatum.ppt
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Transcript condyloma acuminatum.ppt
condyloma acuminatum
1、Definition
Condyloma acuminatum(also known as
condyloma acuminata,genital wart or venereal
warts ) is a proliferative disease caused by
human papillomavirus of some types.
2、etiology
The primary human papillomaviruses(HPV)
that cause condyloma acuminatum are:
HPV-6
HPV-11
HPV-16
HPV-18
all are mucotropic viruses
3、transmission and epidemic
main way of infection : the contact infection is
the main path of the condyloma acuminatum,the
infectivity is the most strong in the stage of about 3
months. Infrequently , it could be spread by
contaminated pants ,bathtub or towels and so on.
It is contracted by close contact without sexual
behaviour in family.
And fetuses are contracted by the infected birth canal
or the close contact with infected mothers.
4、clinical manifestation
The incubation period is 1 to 8 months(usually
3 months) and the leisons appear primarily in and
around the skin or mucous membranes of the
genital area.
Lesions:
The lesions start with soft erythrous tiny papules
which are sarcoid mammilliform ecptomas , range in size
from pinpoint to mung bean,with the rough surface .then
the papules growth into size of peanut kernel ,
cauliflower-like or comb shape-like huge pedunculated
masses develop from mutual confluence ,which are easy
to bleed during sexual life.
Erosion and ulcer may develop when blood supply is not
sufficient in the warts or secondary infection is existing.
Relationship with neoplasmata genitalis
:
It has been confirmed that condyloma
acuminatum is associated with the cancer of the
genital,especially carcinoma cervicis.
The development of about 15% carcinoma
of penis , 5% cancer of vulva and considerable
cancer of anus is on the long-term foundation of
condyloma acuminatum.
5、histopathology
acanthosis
vacuolus bulliform cells are present in the
superficial or superficial middle epidermis ,
trochanterellus is thicking and prolonging with
papillomatous hyperplasia.
6、 diagnosis and differential diagnosis
•sexual behavior outside of the marriage or mate
with a history of infection
•typical lesions
•histopathology inspection when it is necessary
7、 treatment
topical treatment :
•0.5% podophyllotoxin tinctura,2 times daily, 3
days is a course of treatment,repetition needs an
interval of more than 4 days ,pay attention to
preserve the normal skin or mucous membranes
around warts. It can cause abnormal embryos,and
is forbade to using in the pregnant women .
•laser and hypercator cauterize or cut the warts
injecting interferon or transfer factor
for condyloma acuminatum of recurrent
attacks, taking Chinese traditional and
herbal drugs orally,or topical treatment
with interferon cream.
.